## Abstract The p53 tumor suppressor protein is a critical mediator of cell cycle arrest and apoptosis in response to genotoxic stress. Abrogation of p53 function is a major feature of tumor development and may result in a compromised DNAβdamage response. In our study, we examined the effect of exp
β¦ LIBER β¦
Induction of p21 by p53 following DNA damage inhibits both Cdk4 and Cdk2 activities
β Scribed by He, Guangan; Siddik, Zahid H; Huang, Zaifeng; Wang, Ruoning; Koomen, John; Kobayashi, Ryuji; Khokhar, Abdul R; Kuang, Jian
- Book ID
- 110069531
- Publisher
- Nature Publishing Group
- Year
- 2005
- Tongue
- English
- Weight
- 641 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0950-9232
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