✦ LIBER ✦

Lovastatin mediated G1 arrest in normal and tumor breast cells is through inhibition of CDK2 activity and redistribution of p21 and p27, independent of p53

✍ Scribed by Rao, Sharmila; Lowe, Michael; Herliczek, Thaddeus W; Keyomarsi, Khandan

Book ID: 110061779
Publisher: Nature Publishing Group
Year: 1998
Tongue: English
Weight: 444 KB
Volume: 17
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1202322

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

UCN-01-mediated G1 arrest in normal but

UCN-01-mediated G1 arrest in normal but not tumor breast cells is pRb-dependent and p53-independent

✍ Chen, Xiaomei; Lowe, Michael; Keyomarsi, Khandan 📂 Article 📅 1999 🏛 Nature Publishing Group 🌐 English ⚖ 432 KB

Inhibition of cyclin-dependent kinases 2

Inhibition of cyclin-dependent kinases 2 and 4 activities as well as induction of cdk inhibitors p21 and p27 during growth arrest of human breast carcinoma cells by (−)-epigallocatechin-3-gallate

✍ Yu-Chih Liang; Shoei-Yn Lin-Shiau; Chieh-Fu Chen; Jen-Kun Lin 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 160 KB 👁 2 views

Ϫ)-Epigallocatechin-3-gallate (EGCG) potently inhibits cell proliferation and suppresses tumor growth both in vitro and vivo, but little is known regarding the cell cycle regulatory proteins mediating these effects. This study investigated the effects of EGCG and other catechins on the cell cycle pr

p53-independent G1cell cycle arrest of h

p53-independent G1cell cycle arrest of human colon carcinoma cells HT-29 by sulforaphane is associated with induction of p21CIP1and inhibition of expression of cyclin D1

✍ Guoxiang Shen; Changjiang Xu; Chi Chen; Vidya Hebbar; Ah-Ng Tony Kong 📂 Article 📅 2005 🏛 Springer 🌐 English ⚖ 551 KB

CF mediated G1 arrest is associated with

CF mediated G1 arrest is associated with induction of p27Kip1 and inhibition of cyclin D1 expression in human hepatoma HepG2 cells

✍ Ye Jian; Wang JingZe 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 310 KB

Growth arrest by troglitazone is mediate

Growth arrest by troglitazone is mediated by p27Kip1 accumulation, which results from dual inhibition of proteasome activity and Skp2 expression in human hepatocellular carcinoma cells

✍ Wataru Motomura; Nobuhiko Takahashi; Miho Nagamine; Mitsuko Sawamukai; Satoshi T 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 French ⚖ 146 KB

## Abstract In our study, we examined whether human hepatocellular carcinoma (HCC) expresses peroxisome proliferator‐activated receptor γ (PPARγ) and the effects of PPAR γ activation by its selective ligands on cell growth and cell invasion in HCC cells. RT‐PCR and Western blot analysis revealed th

Activation of GPR30 inhibits the growth

Activation of GPR30 inhibits the growth of prostate cancer cells through sustained activation of Erk1/2, c-jun/c-fos-dependent upregulation of p21, and induction of G2 cell-cycle arrest

✍ Chan, Q K Y; Lam, H-M; Ng, C-F; Lee, A Y Y; Chan, E S Y; Ng, H-K; Ho, S-M; Lau, 📂 Article 📅 2010 🏛 Nature Publishing Group 🌐 English ⚖ 946 KB