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Induction of ouabain-resistance mutation and cycle-dependent transformation of C3H/10T1/2 cells by N-nitroso-2-acetylaminofluorene

✍ Scribed by Jen-Kun Lin; Ming-Liang Kuo

Book ID: 113193763
Publisher: Elsevier Science
Year: 1990
Tongue: English
Weight: 681 KB
Volume: 230
Category: Article
ISSN: 0027-5107
DOI: 10.1016/0027-5107(90)90039-7

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## Abstract In order to increase the sensitivity of the C3H/10T1/2 CL8 (10T1/2) cell transformation system, we increased the chemical exposure period to a total of 6 days (two consecutive 3‐day exposures). Using this modified procedure, we transformed 10T1/2 cells with procarcinogens such as aflato