In this study we examined the action of phorbol esters, several phospholipases and retinoids on t h e induction of ornithine decarboxylase (ODC) activity in rat tracheal epithelial cells. 12-0-Tetradecanoylphorbol-13-acetate (TPA) induces ODC activity in these cells in a dose-and time-dependent mann
β¦ LIBER β¦
Induction of ornithine decarboxylase activity in mouse tissues by phorbol ester is effectively blocked by methylglyoxal bis(butylamidinohydrazone)
β Scribed by Hiroshige Hibasami; Tetsuya Tsukada; Satoru Maekawa; Masaki Sakurai; Kunio Nakashima
- Book ID
- 117057400
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 245 KB
- Volume
- 144
- Category
- Article
- ISSN
- 0006-291X
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## Abstract Ornithine decarboxylase (ODC) inductions by cholera toxin and by the phorbol ester tumor promoter, TPA, were compared in wildβtype Chinese hamster ovary (CHO) cells and in mutant cells having altered cyclic AMPβdependent protein kinase activity. The aim of these studies was to determine