The effects of tienilic acid [ 2,3-dichloro-4-(2-thienylcarbonyl)phenoxy acetic acid] on drug-metabolizing enzymes in the rat liver and kidneys were studied. Short-term treatment for 2 weeks (450 mg per kg per day) increased the activity of microsomal epoxide hydrolase at least two-fold in both rat
Induction of nuclear styrene monooxygenase and epoxide hydrolase in rat liver
β Scribed by E. Garattini; G. Gazzotti; M. Salmona
- Publisher
- Springer
- Year
- 1981
- Tongue
- English
- Weight
- 244 KB
- Volume
- 37
- Category
- Article
- ISSN
- 1420-682X
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