Induction of activating mutations in the
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Ming-Qing Du; Paul L. Carmichael; David H. Phillips
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Article
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1994
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John Wiley and Sons
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English
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## Abstract The mutagenicity of oxygen free radicals was studied in a forward mutation system. pEC plasmid containing the human cβHaβ__ras__β1 protoβoncogene was reacted with oxygen free radicals generated by Cu^2+^ and H~2~O~2~ and was then transfected into NIH/3T3 cells. Transformed foci were obs