Induction of metallothionein in mouse liver by valproic acid
β Scribed by Masayuki Kaji; Haruki Mikawa
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 348 KB
- Volume
- 69
- Category
- Article
- ISSN
- 0300-483X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Cadmium is a toxic metal that induces the expression of metallothionein genes in many tissues and that binds avidly to metallothionein, a soluble transition metal binding protein. The present study examined the temporal pattern and magnitude of accumulation of metallothionein mRNA in liver of C57BL
## Abstract ## BACKGROUND Valproic acid (VPA) is an anticonvulsant drug that is widely used therapeutically for a variety of neurological conditions. VPA is also well known for its teratogenic potential in both humans and experimental animal models. The typical malformations observed following VPA