Genetic studies on metallothionein synthesis in the mouse: The induction of metallothionein by cadmium in inbred strains
โ Scribed by David M. Hunt; Tendai Mhlanga
- Publisher
- Springer
- Year
- 1983
- Tongue
- English
- Weight
- 627 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0006-2928
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Cadmium-induced metallothionein (MT) synthesis was investigated in male rats of three ages, 3, 12 and 24 months. Physiological levels of MT in kidney, liver and lung measured simultaneously in untreated animals were found to be within the same range in all three age groups. Following 3-day treatment
Liver and lung metallothionein (MT) levels were increased by endotoxin. The administration of superoxide dismutase (SOD) or allopurinol (ALLO) before (30-60 min) or after (24-32 h) the endotoxin treatment either increased or did not affect the effect of endotoxin on MT levels, depending on the parti