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Induction of lymphangiogenesis through vascular endothelial growth factor-C/vascular endothelial growth factor receptor 3 axis and its correlation with lymph node metastasis in nasopharyngeal carcinoma

โœ Scribed by Naohiro Wakisaka; Kyoko Hirota; Satoru Kondo; Seiko Sawada-Kitamura; Kazuhira Endo; Shigeyuki Murono; Tomokazu Yoshizaki


Book ID
119339211
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
768 KB
Volume
48
Category
Article
ISSN
1368-8375

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## Abstract ## BACKGROUND Vascular endothelial growth factor C (VEGFโ€C) plays an important role in lymphangiogenesis and activates VEGF receptor 3 (VEGFRโ€3). By contrast, lymphatic spread is an important prognostic factor in patients with nonsmall cell lung carcinoma (NSCLC). The objective of the