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Induction of heat shock proteins in young and senescent human diploid fibroblasts

✍ Scribed by Yoshiaki Tsuji; Sadahiko Ishibashi; Toshinori Ide

Book ID
119025740
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
479 KB
Volume
36
Category
Article
ISSN
0047-6374

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## Abstract Induction of the heat shock response (HSR), determined by hsp70‐luciferase reporter and HSP70 protein expression, is attenuated as a function of age of the IMR‐90 human diploid fibroblasts. To better understand the underlying mechanism, we evaluated changes in the regulation and functio