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Induction of Heat Shock Proteins by Hyperthermia and Noise Overstimulation inHsf1−/−Mice

✍ Scribed by Tzy-Wen Gong; Damon A. Fairfield; Lynne Fullarton; David F. Dolan; Richard A. Altschuler; David C. Kohrman; Margaret I. Lomax


Book ID
106290642
Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
271 KB
Volume
13
Category
Article
ISSN
1525-3961

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Heat shock proteins (Hsps) can enhance cell survival in response to stress. Heat shock factor 1 (Hsf1) is the major transcription factor that regulates stress-inducible Hsp expression. We previously demonstrated the presence of Hsf1 in the rodent cochlea and also demonstrated that a heat shock known