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Induction of Functional Differentiation and Growth Inhibition In Vitro of Canine Osteosarcoma by 22-Oxacalcitriol, Calcitriol and All-trans Retinoic Acid

✍ Scribed by Barroga, E. ;Kadosawa, T. ;Okumura, M. ;Fujinaga, T.

Book ID: 114430127
Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 187 KB
Volume: 46
Category: Article
ISSN: 0931-184X
DOI: 10.1046/j.1439-0442.1999.00251.x

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## Abstract Retinoids play essential roles in the regulation of cell differentiation and in the proliferation of various epithelial tissues, and atRA is one such active metabolite of retinoids. However, despite the known functions of atRA, its clinical applications are limited due to the induced me