Mating type interconversion of the yeast, Saccharomyces cerevisiae, is an example of a directed genome rearrangement leading to a change in gene expression and in the differentiation state of a cell. In heterothallic haploid cells this switching of the mating type from a to alpha or vice versa, whic
Induction of DNA damage and apoptosis in Saccharomyces cerevisiae by a yeast killer toxin
โ Scribed by Roland Klassen; Friedhelm Meinhardt
- Book ID
- 109037147
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 317 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1462-5814
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A chimeric plasmid (pYT760-ADHl) containing the yeast killer toxin-immunity cDNA w a s transformed into a leucine-histidine mutant (AH22) and into four industrial toxin-sensitive yeasts. The chimeric plasmid w a s very stable and expressed toxin production (89.5 -+4.8% killer cells) in two of the tr