Induction of differentiation in HL-60 cells by retinoic acid and lymphocyte-derived differentiation-inducing factor but not by recombinant G-CSF and GM-CSF

Purified colony stimulating factors (G-C

Purified colony stimulating factors (G-CSF and GM-CSF) induce differentiation in human HL60 leukemic cells with suppression of clonogenicity

✍ C. Glenn Begley; Donald Metcalf; Nicos A. Nicola 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 French ⚖ 854 KB

Purified recombinant human granulocyte-macrophage col- HL60 (Metcalf, 1983) and similar results were observed using ony-stimulating factor (rHGM-CSF) and purified native mu-comparable material from other media containing human CSFs rine granulocyte-CSF (G-CSF) both induced differentiation in (plaker