Induction of cytotoxic T-cell responses in vivo in the absence of CD4 helper cells
✍ Scribed by Buller, R. Mark L.; Holmes, Kevin L.; Hügin, Ambros; Frederickson, Torgny N.; Morse, Herbert C.
- Book ID
- 109749893
- Publisher
- Nature Publishing Group
- Year
- 1987
- Tongue
- English
- Weight
- 357 KB
- Volume
- 328
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/328077a0
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Receptors for conserved molecular patterns associated with microbial pathogens induce synthesis of co-stimulatory molecules and cytokines in immature dendritic cells (DC), as do antigen-reactive CD4 T helper cells via CD40 signaling. Once activated, antigen-presenting DC may activate CD8 T cell resp
## Afferent lymph veiled cells prime CD4+ T cell responses in vivo The interdigitating cell (IDC) population of the lymph node paracortex is believed to be responsible for the induction of CD4+ T cell responses to soluble antigens. We have examined the role of afferent lymph veiled cells (ALVC), t