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Induction of cytochromes P-450 in pancreatic disease: Consequence, coincidence or cause?

✍ Scribed by David W.K. Acheson; Patricia Rose; J.Brian Houston; Joan M. Braganza


Book ID
115825046
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
827 KB
Volume
153
Category
Article
ISSN
0009-8981

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Cytochrome P450 2E1 (CYP2E1) may be a central pathway in generating oxidative stress, reactive oxygen species, and causing hepatotoxic injury by alcohol and various hepatotoxins. This study evaluated the ability of CYP2E1 to potentiate or synergize the hepatotoxicity of Fas in vivo. C57BL/6 mice wer