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Difference between species in response to a 3,5‐dichloropyridyloxyphenoxy compound: Induction of cytochrome P‐450 and/or peroxisome proliferation†

✍ Scribed by Schmidt, U.; Machemer, L.


Book ID
121269518
Publisher
Taylor and Francis Group
Year
1989
Tongue
English
Weight
739 KB
Volume
6
Category
Article
ISSN
0265-203X

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Six species (CD-1 mouse, Fischer 344 rat, Syrian golden hamster, Duncan-Hartley guinea pig, half-lop rabbit and marmoset monkey) were treated orally with ciprofibrate, a potent oxyisobutyrate hypolipidaemic drug for 14 days. A dosedependent liver enlargement was observed in the mouse and rat and at