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Induction of Cytochrome P4503A by Taxol in Primary Cultures of Human Hepatocytes

โœ Scribed by Vsevolod E. Kostrubsky; Lionel D. Lewis; Stephen C. Strom; Sheryl G. Wood; Erin G. Schuetz; John D. Schuetz; Peter R. Sinclair; Steven A. Wrighton; Jacqueline F. Sinclair


Book ID
115567186
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
191 KB
Volume
355
Category
Article
ISSN
0003-9861

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โœ Edward L. LeCluyse; Ajay Madan; Geraldine Hamilton; Kathy Carroll; Ryan DeHaan; ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 339 KB ๐Ÿ‘ 1 views

The aim of this study was to test suitable culture conditions for maintaining normal cellular cytoarchitecture and inducibility of P450 enzymes in primary cultures of human hepatocytes by prototypical inducers. The selectivity and sensitivity of a sandwich culture system were determined by treating