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Induction of cytochrome P-450 by phenobarbital is mediated at the level of transcription

โœ Scribed by Susan F. Pike; Elizabeth A. Shephard; Brian R. Rabin; Ian R. Phillips

Book ID
115778420
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
597 KB
Volume
34
Category
Article
ISSN
0006-2952

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๐Ÿ“œ SIMILAR VOLUMES

Phenobarbital induction of cytochrome p-
Phenobarbital induction of cytochrome p-450 b,e genes is dependent on protein synthesis
โœ Jose Chianale; Leyna Mulholland; Peter G. Traber; Jorge J. Gumucio ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 635 KB

Phenobarbital induces liver cytochrome P-450 b,e proteins mainly by increasing the rate of transcription of these genes. The mechanism responsible for the phenobarbital increment in the rate of transcription of cytochrome P-450 b,e genes is unknown. The objective of this study was to assess whether