𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Induction of cell differentiation in burkitt lymphoma lines. BLA: A glycolipid marker of B-cell differentiation

✍ Scribed by Anne Balana; Joëlle Wiels; Cécile Tetaud; Thomas Tursz; Zohar Mishal

Publisher
John Wiley and Sons
Year
1985
Tongue
French
Weight
667 KB
Volume
36
Category
Article
ISSN
0020-7136

No coin nor oath required. For personal study only.

✦ Synopsis

We have previously described an MAb referred to as 38.13 which reacts with a glycolipid membrane antigen (named BLA) on Burkitt lymphoma (BL) lines. The BLA antigen and other 6-cell differentiation markers have been studied on BL lines treated with sodium butyrate, agents from the phorbol-diester series (with or without differentiating properties) and teleocidin. With all differentiation inducers tested, expression of BLA as well as of surface IgM decreased on the induced cells whereas that of BI increased and that of HLA D R remained stable. No BL cells studied reacted with anti-IgD, with BZ or with LBI MAbs, either before or after induction. An EBV-negative line (BJAB) was compared to its Epstein-Barr virus (EBV)converted subline (BJAWB95). Both EBV-positive and EBV-negative lines gave comparable results. These data demonstrate that BL cells could be moved along their differentiation pathway by chemical inducers and suggest that BLA represents a new glycolipid marker of early 6-cell differentiation.

📜 SIMILAR VOLUMES

Differential regulation of glycosphingol
Differential regulation of glycosphingolipid biosynthesis in phenotypically distinct Burkitt's lymphoma cell lines
✍ Samir Taga; Marianne Mangeney; Thomas Tursz; Joëlle Wiels 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 875 KB

Earlier studies have shown that Burkitt's lymphoma (BL) cell lines can be divided into 2 major groups: group I. which retain the original BL biopsy phenotype with expression of CD I0 and CD77 antigens and lack of B-cell activation markers, and group 111, which, after several in vitro passages, progr

High-resolution analysis of chromosome m
High-resolution analysis of chromosome markers in burkitt lymphoma cell lines
✍ Sichong Zhang; Lore Zech; George Klein 📂 Article 📅 1982 🏛 John Wiley and Sons 🌐 French ⚖ 600 KB

## Abstract Using a high‐resolution chromosome banding technique, which provided more elongated and distinctly banded chromosomes, some new evidence was obtained for localization of break points in Burkitt lymphoma marker chromosomes. As a result, the characteristic translocation between chromosome

Expression of B-cell-specific markers in
Expression of B-cell-specific markers in different burkitt lymphoma subgroups
✍ Barbro Ehlin-Henriksson; Agneta Manneborg-Sandlund; George Klein 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 French ⚖ 702 KB

Forty-three Burkitt lymphoma (BL) lines were examined for the expression of 5 monoclonal antibody (MAb)-identified B-cell-specific markers and immunoglobulin production. All (13) EBV-negative BL lines were CALLA+ LB-1-, whereas 30 EBV-carrying lines showed a more heterogeneous pattern. In the EBV-ne

Characterization of immunoglobulin mrna
Characterization of immunoglobulin mrna expression in burkitt lymphoma cell lines
✍ Roberto Anker; James Caldwell; Jane Brokaw; Brian A. Pollok 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 French ⚖ 912 KB

Immunoglobulin heavy-and light-chain mRNA of I I Burkitt lymphoma (BL) cell lines (9 African and 2 American) were analyzed for various structural characteristics. In agreement with previous results at the protein level, all the BIL cell lines express heavy-chain mRNA transcripts of the p class. Surp

Differential induction of cell death in
Differential induction of cell death in human glioma cell lines by sodium nitroprusside
✍ Robert V. Blackburn; Sandra S. Galoforo; Christine M. Berns; Nalini M. Motwani; 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 164 KB 👁 2 views

## Background: High grade gliomas represent very aggressive and lethal forms of human cancer, which often exhibit recurrence after surgical intervention and resistance to conventional chemotherapeutic and radiologic treatment. the clinically approved antihypertensive agent sodium nitroprusside (snp