Induction of cell death by endogenous nerve growth factor through its p75 receptor
✍ Scribed by María Frade, José; Rodríguez-Tébar, Alfredo; Barde, Yves-Alain
- Book ID
- 109797855
- Publisher
- Nature Publishing Group
- Year
- 1996
- Tongue
- English
- Weight
- 743 KB
- Volume
- 383
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/383166a0
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
In our preceding report, we have shown that nerve growth factor (NGF) and its low-affinity receptor (p75 NTR ) are expressed in C2C12 myoblasts and downregulated during myogenic differentiation. Furthermore, NGF affects myogenic differentiation and cell growth via p75 NTR and downregulation of p75 N
Mutant PC12 cell clones (PC84 cells) were obtained by transfection with nerve growth factor (NGF) cDNA. These cells secreted active NGF, extended short processes, and proliferated faster than the parental PC12 cells. These features are of great interest because the parental PC12 cells cease prolifer
The childhood ceroid-lipofuscinoses are a group of autosomal recessively inherited disorders characterized by massive accumulation of autofluorescent lysosomal storage bodies in neurons as well as other cell types. The storage body accumulation is accompanied by severe degeneration of the central ne
## Abstract The loss of tumor‐ and/or metastasis‐suppressor gene function contributes to the transformation of human prostate epithelial cells to a malignant pathology. Such a putative tumor‐suppressor and metastasis‐suppressor gene(s) has been mapped to the region of 17q21, which coincidentally is