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Induction of CD8 antigen and suppressor activity by glucocorticoids in a CEM human leukemic cell clone

✍ Scribed by Laurence Danel-Moore; Simon Kawa; Gulgun D. Kalmaz; David Bessman; E.Brad Thompson


Book ID
113239801
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
540 KB
Volume
17
Category
Article
ISSN
0145-2126

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Glutamine synthetase induction by glucoc
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## Abstract Treatment of CEM‐C7 cells with glucocorticoids produces a 2.5‐fold increase in the activity of the enzyme glutamine synthetase (GS). This increase is specific for steroids with glucocorticoid activity and occurs over a range of steroid concentrations consistent with a receptor‐mediated