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Induction of apoptosis and inhibition of telomerase activity by trichostatin A, a histone deacetylase inhibitor, in human leukemic U937 cells

✍ Scribed by Hyun Joo Woo; Su Jae Lee; Byung Tae Choi; Yeong-Min Park; Yung Hyun Choi


Book ID
113956446
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
806 KB
Volume
82
Category
Article
ISSN
0014-4800

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Reduction of telomerase activity in huma
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## Abstract The presence of telomerase has been demonstrated recently in many different malignancies. Several reports documented that in human hepatocellular carcinoma, the level of telomerase activity parallels its differentiation stage. In the present study, the effect of the differentiation‐indu