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Induction of Cancer Cell Death by Self-assembling Nanostructures Incorporating a Cytotoxic Peptide

✍ Scribed by Cheng, H.; Soukasene, S.; Chen, J.; Raja, S. M.; Band, V.; Band, H.; Cryns, V. L.; Stupp, S. I.; Toft, D. J.; Standley, S. M.


Book ID
111924230
Publisher
American Association for Cancer Research
Year
2010
Tongue
English
Weight
562 KB
Volume
70
Category
Article
ISSN
0008-5472

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## Abstract __Annonaceous acetogenins are a family of natural products with antitumor activities. The polyether mimic AA005 has been synthesized. The cytotoxic mechanism of AA005 was investigated. It was found that AA005 can induce the cell death of gastric tumor cells. Most AA005‐induced cell deat