Induction of apoptotic cell death by a ceramide analog in PC-3 prostate cancer cells
β Scribed by Ji Eun Oh; Kwang Sup So; Se Jin Lim; Mie Young Kim
- Book ID
- 105671035
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 943 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0253-6269
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## Background: More than 95% of metastatic androgen independent prostatic cancer cells per day are in a proliferatively quiescent g0 state [berges et al.: clin cancer res 1:473-480, 1995] limiting their responsiveness to anti-proliferative chemotherapeutic agents. novel therapeutics capable of acti
## Abstract The hormonalβregulated serpin, ovine uterine serpin (OvUS), also called uterine milk protein (UTMP), inhibits proliferation of lymphocytes and prostate cancer (PCβ3) cells by blocking cellβcycle progression. The present aim was to identify cellβcycleβrelated genes regulated by OvUS in P