## Abstract The cโmet protoโoncogene encodes the receptor to hepatocyte growth factorโscatter factor (HGFโSF), a mesenchymeโderived cytokine with cellโdissociating, invasion, and angiogenic properties. The expression of cโmet in breast cancer is the subject of controversy; 111 primary breast cancer
Induction of c-met proto-oncogene expression at the metastatic site
โ Scribed by Jun-ichi Imai; Manabu Watanabe; Masahide Sasaki; Ryoji Yamaguchi; Susumu Tateyama; Sumio Sugano
- Book ID
- 110239297
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 93 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0262-0898
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mal and malignant epithelial cells and several other cell The c-met proto-oncogene encodes the tyrosine kinase types, including endothelial cells and melanocytes. 4,5 receptor for hepatocyte growth factor (HGF), a potent It has been reported that the expression of c-Met is enmitogen and motogen for
The c-met proto-oncogene encodes the tyrosine kinase receptor for hepatocyte growth factor (HGF), a potent mitogen and motogen for epithelial cells. Because of its profound effects on cell growth and motility, HGF may be important in the development of cancer metastases in hepatocellular carcinoma (