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Induction of bleomycin resistance in a human oral squamous carcinoma cell line and characterisation of bleomycin-resistant and -sensitive clones

✍ Scribed by Urade, M.; Ogura, T.; Uematsu, T.; Takahashi, Y.; Kishimoto, H.; Yoshioka, W.


Book ID
122537533
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
653 KB
Volume
30
Category
Article
ISSN
0964-1955

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## Abstract ## Background Resistance to chemotherapy is a major limitation in the treatment of head and neck squamous cell carcinomas (HNSCCs), accounting for high mortality rates in patients. Here, we investigated the role of replication protein A (RPA) in cisplatin and etoposide resistance. ##