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Induction of B lymphocytes by helper T cells: Requirement of direct cell contact

โœ Scribed by Martinez-A, C.; De La Hera, A.; Marquez, C.; Pereira, P.


Book ID
123386541
Publisher
Elsevier Science
Year
1984
Weight
307 KB
Volume
135
Category
Article
ISSN
0769-2625

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We have analyzed the role of cognate interaction with helper T cells (Th) in support of resting B cell differentiation to plaque formation. Co-culture of histoincompatible resting B cells and resting Th cells resulted in the induction of plaque-forming cells when dimeric but not monomeric fragments