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Induction of Apoptosis in Human Replicative Senescent Fibroblasts

✍ Scribed by Vimaris DeJesus; Ileana Rios; Claudette Davis; Yengsi Chen; David Calhoun; Zahra Zakeri; Karen Hubbard


Book ID
115604185
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
388 KB
Volume
274
Category
Article
ISSN
0014-4827

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## Abstract The proteasome constitutes the main non‐lysosomal cellular protease activity, and plays a crucial role not only in the disposal of unwanted material, but also in the regulation of numerous cellular processes. Previously, we have reported that during the replicative senescence of WI‐38 f