Induction of thymocyte apoptosis by syst
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Raja Fayad; Joseph A. Sennello; Soo-Hyun Kim; Maria Pini; Charles A. Dinarello;
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Article
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2005
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John Wiley and Sons
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English
⚖ 484 KB
Administration of concanavalin A (Con A) is a well-established model of acute immune-mediated hepatitis. Here, we demonstrate that intravenous injection of Con A in mice induces profound thymic atrophy. Compared to liver damage, the kinetics of Con A-induced thymic atrophy is slower and more prolong