## Abstract The original article to which this Erratum refers was published in International Journal of Cancer (2003) 106(2) 160โ166
Induction of apoptosis by phenethyl isothiocyanate in cells overexpressing Bcl-XL
โ Scribed by Sarah L. Cuddihy; Kristin K. Brown; Susan J. Thomson; Mark B. Hampton
- Book ID
- 116334877
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 327 KB
- Volume
- 271
- Category
- Article
- ISSN
- 0304-3835
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## Abstract Our study was designed to investigate the role of the antiโapoptotic proteins Bclโ2 and BclโxL in the chemoresistance of cells derived from malignant pleural mesothelioma. First, we determined the basal expression levels of Bclโ2 and BclโxL in mesothelioma cells and examined the effect
Over-expression of the anti-apoptotic protein bcl-xL is frequently found in lung cancer where it potentially contributes to tumor development, progression and drug resistance. To override the apoptotic block in lung-adenocarcinoma and small-cell-lung-cancer (SCLC) cells caused by over-expression of