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Induction of apoptosis by 2-chlorodeoxyadenosine in B cell chronic lymphocytic leukemia

✍ Scribed by Castejón, R; Vargas, J A; Briz, M; Berrocal, E; Romero, Y; Gea-Banacloche, J C; Fernández, M N; Durántez, A

Book ID
110053563
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
294 KB
Volume
11
Category
Article
ISSN
0887-6924

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## Abstract The cytotoxic effects and the induction of programmed cell death (apoptosis) by Fludarabine (FLU), 2‐chlorodeoxyadenosine (2‐CdA), and deoxycoformycin (DCF) with/without α‐interferon (α‐IFN) were evaluated in vitro against freshly isolated B‐chronic lymphocytic leukemia (B‐CLL) cells. C