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Induction mechanisms of cytochrome P450 2E1 in liver: Interplay between ethanol treatment and starvation

✍ Scribed by Hu Yin; Magnus Ingelman-Sundberg; Kai O. Lindros

Book ID
115784279
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
747 KB
Volume
50
Category
Article
ISSN
0006-2952

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The release of proinflammatory cytokines by endotoxins and during oxidative stress is considered to be an early key step in the pathogenesis of alcoholic liver disease (ALD). Ethanol-inducible cytochrome P450 2E1 (CYP2E1) has potentially pro-oxidative and toxicological properties, and its expression