Induction chemotherapy and radiotherapy in loco-regionally advanced epidermoid carcinoma of the anal canal
β Scribed by Christer Svensson; Sven Goldman; Bertil Friberg; Bengt Glimelius
- Book ID
- 108437121
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 73 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0360-3016
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During the last decade conservative treatment of anal carcinoma based on radiotherapy has gained popularity. Radiotherapy is often combined with concurrent chemotherapy although no firm evidence exists that such combinations are more effective than radiotherapy alone. Treatment results with respect
Between 1985 and 1992, 46 patients with epidermoid carcinoma of the anal canal were treated prospectively by a protocol of combined radiation and chemotherapy with 5-Fluorouracil and Mitomycin C. The survival rate, NED-survival rate and local tumour control rate were 84%, 71% and 83% at 5 years. Ano