𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Induction and/or selective retention of proteins in mammalian cells exposed to cycloheximide

✍ Scribed by V. Sorrentino; A. Battistini; A. M. Curatola; P. Di Francesco; G. B. Rossi

Book ID
102880501
Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
672 KB
Volume
125
Category
Article
ISSN
0021-9541

No coin nor oath required. For personal study only.

✦ Synopsis

Exposure of a number of murine and human cell lines to low graded doses of cycloheximide (CXM) results in a pattern of protein synthesis consisting of enhanced and induced species. These can be divided into two main classes according to molecular weight (20-40 and 70-120 Kd), similar to what has been described for other agents that modify the physiological conditions of growth. In addition, the pronounced synthesis of a hitherto unreported 50-Kd protein species has been consistently observed in all lines tested. Simultaneous exposure of cells to CXM and actinomycin D results in suppressing synthesis of some but not all protein species observed, indicating that control mechanisms at both transcriptional and posttranscriptional levels may be operative in this system.

πŸ“œ SIMILAR VOLUMES

Stress proteins are not induced in mamma
Stress proteins are not induced in mammalian cells exposed to radiofrequency or microwave radiation
✍ Stephen F. Cleary; Guanghui Cao; Li-Ming Liu; Patsy M. Egle; Keith R. Shelton πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 91 KB

The induction of stress proteins in HeLa and CHO cells was investigated following a 2 h exposure to radiofrequency (RF) or microwave radiation. Cells were exposed or sham exposed in vitro under isothermal (37 { 0.2 ЊC) conditions. HeLa cells were exposed to 27-or 2450 MHz continuous wave (CW) radiat

Induction of fatty acid synthesis in cul
Induction of fatty acid synthesis in cultured mammalian cells: Effects of cycloheximide and x-rays
✍ R. A. Raff πŸ“‚ Article πŸ“… 1970 πŸ› John Wiley and Sons 🌐 English βš– 784 KB

## Abstract It was found that L cells deprived of exogenous fatty acids responded adaptively by increased synthesis of fatty acids. This adaptive increase was found to be sensitive to cycloheximide presented at the time of removal of exogenous lipids, but was not sensitive to cycloheximide added si