Induction and genetical analysis of edeine resistant mutants of Neurospora crassa
✍ Scribed by Teles Grilo, Maria Leonor ;Klingmüller, Walter
- Publisher
- Springer
- Year
- 1974
- Tongue
- English
- Weight
- 757 KB
- Volume
- 133
- Category
- Article
- ISSN
- 0026-8925
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Non-saponifiable cell extracts of wild type and sterol mutants of N. crassa were analysed by means of gas-liquid chromatography. The wild-type contained ergosterol and episertol in a 10:1 ratio. None of the mutants was able to synthesize ergosterol. Three of the mutants carry single recessive gene m
The effect of edeine and the mutation edr-2 to edeine resistance on genetic recombination in Neurospora crassa was investigated. For this purpose crosses between pairs of edeine sensitive and edeine resistant strains respectively were set up without or in the presence of the drug (0-750 microg/ml).