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Inducible nitric oxide synthase following hypoxia in rat cultured glial cells

โœ Scribed by Makoto Kawase; Hiroyuki Kinouchi; Ichiro Kato; Atsuya Akabane; Takeo Kondo; Shouichi Arai; Miki Fujimura; Hiroshi Okamoto; Takashi Yoshimoto

Book ID
114001913
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
654 KB
Volume
738
Category
Article
ISSN
0006-8993

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Lipopolysaccharide (LPS) or a combination of interleukin (IL)-lp and interferon (1FN)-y cause transcriptional induction of a calcium-independent nitric oxide synthase (NOS) in astrocytes and C6 glioma cells. LPS induction of NOS in C6 cells was evidenced by a small amount of nitrite accumulation as