Inducible expression of granulocyte-macrophage colony-stimulating factor, tumor necrosis FACTOR-α, and INTERFERON-γ in two human cytotoxic leukemic T-cell lines
✍ Scribed by Alessandra Cesano; Daniela Santoli
- Book ID
- 112801649
- Publisher
- Society for In Vitro Biology
- Year
- 1992
- Tongue
- English
- Weight
- 641 KB
- Volume
- 28
- Category
- Article
- ISSN
- 1475-2689
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## Abstract Receptors for granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) were identified on 9 of 35 (26%) human nonhematopoietic tumor cell lines including non‐small cell lung cancer, stomach cancer, colon cancer, and osteosarcoma cells. GM‐CSF receptors distributed on these human tumor
Interleukin 1 and tumor necrosis factor-a additively increase the levels of granulocyte-macrophage and granulocyte colony-stimulating factor (CSF) mRNA in human fibroblasts\* Recombinant interleukin (IL) 1 p and tumor necrosis factorkachectin (TNF-a) induce, usually within 2 h, a dose-dependent incr