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Induced mutagenesis in ataxia-telangiectasia (AT) heterozygote cells

✍ Scribed by Yu.E. Ivanova

Book ID
113250357
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
60 KB
Volume
97
Category
Article
ISSN
0165-1161

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Epidemiological studies have suggested that ataxia-telangiectasia (AT) heterozygotes have a predisposition to cancer, especially breast cancer in women. Now, haplotyping can identify heterozygotes for AT mutation (ATM) in AT families, allowing the risk of cancer associated with ATM heterozygosity st