Target selection for antisense oligonucl
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Stephen J. Errington; Christopher J. Mann; Sue Fletcher; Dr Stephen D. Wilton
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Article
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2003
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John Wiley and Sons
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English
β 308 KB
## Abstract ## Background Duchenne muscular dystrophy (DMD) is an Xβlinked recessive muscle wasting disorder characterised by the absence of the protein dystrophin. Antisense oligonucleotides have been used to reβdirect dystrophin preβmRNA processing by blocking sequences crucial to preβmRNA splic