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T.P.2.09 Induced exon skipping in normal and mdx muscle

✍ Scribed by S. Fletcher; J.P. Steinhaus; C. Mitrpant; P.L. Meloni; S.D. Wilton

Book ID
116793537
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
60 KB
Volume
18
Category
Article
ISSN
0960-8966

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Improved antisense oligonucleotide induc
Improved antisense oligonucleotide induced exon skipping in the mdx mouse model of muscular dystrophy
✍ Christopher J. Mann; Kaite Honeyman; Graham McClorey; Sue Fletcher; Stephen D. W πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 299 KB

## Abstract ## Background Duchenne muscular dystrophy (DMD) is a fatal genetic disorder caused by dystrophin gene mutations that preclude synthesis of a functional protein. One potential treatment of the disorder has utilised antisense oligoribonucleotides (AOs) to induce removal of disease‐associ