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Induced color changes in grapefruit and orange

✍ Scribed by H. Yokoyama; C. DeBenedict; C.W. Coggins; G.L. Henning


Publisher
Elsevier Science
Year
1972
Tongue
English
Weight
350 KB
Volume
11
Category
Article
ISSN
0031-9422

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Previous studies with rats indicate that nifedipine undergoes both hepatic and extrahepatic presystemic metabolism after peroral (po) administration, and that its bioavailability is increased and absorption delayed by concomitant administration of grapefruit juice concentrate (GJC). Hence, the effec