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Indoleamine 2,3-dioxygenase: Antioxidant enzyme in the human eye

✍ Scribed by Halina Zofia Malina; Xavier Daniel Martin


Book ID
112775192
Publisher
Springer-Verlag
Year
1996
Tongue
English
Weight
480 KB
Volume
234
Category
Article
ISSN
0065-6100

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## Abstract Human indoleamine 2,3‐dioxygenase (hIDO), a monomeric heme enzyme, catalyzes the oxidative degradation of L‐tryptophan (L‐Trp) and other indoleamine derivatives. Its activity follows typical Michaelis–Menten behavior only for L‐Trp concentrations up to 50 ΞΌM; a further increase in the c