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Indole-3-carbinol and 3,3′-diindolylmethane induce expression of NAG-1 in a p53-independent manner

✍ Scribed by Seong-Ho Lee; Jong-Sik Kim; Kiyoshi Yamaguchi; Thomas E. Eling; Seung Joon Baek


Book ID
117981600
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
378 KB
Volume
328
Category
Article
ISSN
0006-291X

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## Abstract The phytochemical indole‐3‐carbinol (I3C), from cruciferous vegetables such as broccoli, has been shown to elicit a potent anti‐proliferative response in human breast cancer cell lines. Treatment of the immortalized human mammary epithelial cell line MCF10A with I3C induced a G1 cell cy