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UP-03.62: Indole-3-carbinol and 3,3’ diindolylmethane induce apoptosis in human prostate cancer cells

✍ Scribed by A. Stein; B. Appel; M. Nachshon; A. Haj; F. Fares


Book ID
116947026
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
73 KB
Volume
68
Category
Article
ISSN
0090-4295

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## Abstract In the present studies, we utilized prostate cancer cell culture models to elucidate the mechanisms of action of broccoli‐derived phytochemicals 3,3′‐diindolylmethane (DIM) and indole‐3‐carbinol (I3C). We found DIM and I3C at 1–5 µM inhibited androgen and estrogen‐mediated pathways and