A procedure was developed for the determination of mercurials of pharmaceutical interest. Protic acid cleavage of the compound was followed by reduction of the resulting mercuric ion and vapor phase atomic absorption spectroscopy. This procedure was applied to 11 different mercurial compounds in var
Indirect continuous automatic determination of pharmaceuticals by atomic absorption spectroscopy
✍ Scribed by M. Valcárcel; M. Gallego; R. Montero
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 473 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0731-7085
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✦ Synopsis
The implementation of continuous separation techniques such as precipitation, liquid-liquid and solid-liquid extraction in FIA manifolds coupled on-line with an atomic absorption spectrometer for the determination of active components (sulphonamides, local anaesthetics, amphetamines, benzodiazepines, chloramphenicol and methadone) in pharmaceuticals and biological fluids is systematically described. The basic features of the analytical methodologies described (sensitivity, selectivity, precision and rapidity) are also discussed and critically compared.
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