The implementation of continuous separation techniques such as precipitation, liquid-liquid and solid-liquid extraction in FIA manifolds coupled on-line with an atomic absorption spectrometer for the determination of active components (sulphonamides, local anaesthetics, amphetamines, benzodiazepines
Determination of mercury-containing pharmaceuticals by vapor phase atomic absorption spectroscopy
β Scribed by Richard D. Thompson; Terry J. Hoffmann
- Publisher
- John Wiley and Sons
- Year
- 1975
- Tongue
- English
- Weight
- 475 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
β¦ Synopsis
A procedure was developed for the determination of mercurials of pharmaceutical interest. Protic acid cleavage of the compound was followed by reduction of the resulting mercuric ion and vapor phase atomic absorption spectroscopy. This procedure was applied to 11 different mercurial compounds in various pharmaceutical preparations and offers excellent sensitivity with respect to presently used compendial assays. Comparative analytical data between this procedure and compendial methodology are presented. Keyphrases 0 Mercurials-determination by vapor phase atomic absorption spectroscopy, compared to compendial methods 0 Atomic absorption spectroscopy, vapor phase-determination, mercury-containing pharmaceuticals, compared to compendial methods
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