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Determination of mercury-containing pharmaceuticals by vapor phase atomic absorption spectroscopy

✍ Scribed by Richard D. Thompson; Terry J. Hoffmann


Publisher
John Wiley and Sons
Year
1975
Tongue
English
Weight
475 KB
Volume
64
Category
Article
ISSN
0022-3549

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✦ Synopsis


A procedure was developed for the determination of mercurials of pharmaceutical interest. Protic acid cleavage of the compound was followed by reduction of the resulting mercuric ion and vapor phase atomic absorption spectroscopy. This procedure was applied to 11 different mercurial compounds in various pharmaceutical preparations and offers excellent sensitivity with respect to presently used compendial assays. Comparative analytical data between this procedure and compendial methodology are presented. Keyphrases 0 Mercurials-determination by vapor phase atomic absorption spectroscopy, compared to compendial methods 0 Atomic absorption spectroscopy, vapor phase-determination, mercury-containing pharmaceuticals, compared to compendial methods


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