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Independent control of cell survival by Raf-1 and Bcl-2 at the mitochondria

✍ Scribed by Zhong, J; Troppmair, J; Rapp, Ulf R


Book ID
110064874
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
309 KB
Volume
20
Category
Article
ISSN
0950-9232

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To investigate the mechanisms responsible for survival and apoptosis/anoikis in normal human intestinal epithelial crypt cells, we analyzed the roles of various signaling pathways and cell adhesion on the expression of six Bcl-2 homologs (Bcl-2, Bcl-XL, Mcl-1, Bax, Bak, Bad) in the well established