Indenoquinolines. III. Derivatives of 11H-Indeno[1,2-b]quinoxaline and Related Indenoquinolines
✍ Scribed by Pearson, Barry D.; Mitsch, Ronald A.; Cromwell, Norman H.
- Book ID
- 124048426
- Publisher
- American Chemical Society
- Year
- 1962
- Tongue
- English
- Weight
- 630 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0022-3263
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## Abstract New spiro[indeno[1,2‐b]quinoxaline‐11,2′‐pyrrolidine] derivatives were prepared in high yield stereoselectively from an efficient multicomponent 1,3‐dipolar cycloaddition reaction between ninhydrin, phenylenediamine, sarcosine, and chalcones. The regiochemistry and stereochemistry of re
## Abstract A sequential one‐pot four‐component reaction for the efficient synthesis of novel 2′‐aminospiro[11__H__‐indeno[1,2‐__b__]quinoxaline‐11,4′‐[4__H__]pyran] derivatives **5** in the presence of AcONH~4~ as a neutral, inexpensive, and dually activating catalyst is described (__Scheme 1__).