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An efficient multicomponent and stereoselective synthesis of new spiro[indeno[1,2-b]quinoxaline-11,2′-pyrrolidine] derivatives

✍ Scribed by Mehdi Moemeni; Hamid Arvinnezhad; Saadi Samadi; Mahmood Tajbakhsh; Khosrow Jadidi; Hamid Reza Khavasi

Book ID: 102344213
Publisher: Journal of Heterocyclic Chemistry
Year: 2011
Tongue: English
Weight: 277 KB
Volume: 49
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.685

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✦ Synopsis

Abstract

New spiro[indeno[1,2‐b]quinoxaline‐11,2′‐pyrrolidine] derivatives were prepared in high yield stereoselectively from an efficient multicomponent 1,3‐dipolar cycloaddition reaction between ninhydrin, phenylenediamine, sarcosine, and chalcones. The regiochemistry and stereochemistry of resultant cycloadducts have been determined by several 2D NMR spectroscopic techniques and X‐ray single crystal diffraction. J. Heterocyclic Chem., (2012).

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